Canon Medical Systems USA Inc. has received 510(k) clearance for the Aquilion ONE/PRISM Edition, enabling Deep Learning Spectral capabilities that allow for more routine spectral imaging. Designed for deep intelligence, the advanced system integrates artificial intelligence (AI) technology to maximize conventional and spectral CT capabilities with automated workflows, while providing deep clinical insights to assist physicians in making more informed decisions across the patient’s care cycle. An innovative approach to CT reconstruction, Advanced intelligent Clear-IQ Engine (AiCE) on the Aquilion ONE/PRISM Edition uses Deep Learning to distinguish true signal from noise to deliver sharp, clear and distinct images at fast speeds. Trained using vast amounts of high-quality image data, AiCE provides enhanced anatomical resolution across the whole body including brain, lung, cardiac and musculoskeletal applications.